Of note, there was also no evidence that Cd4Cre/+Arg1flox/flox mice were more susceptible to virus-induced autoimmunity, as indicated by anti-Sjögrens syndrome antigen (SSA) titers comparable to those observed in Cd4+/+Arg1flox/flox mice (Figure 4—figure supplement 1D). Here, CD4 is linked to Autoimmunity.