TKT and neoplasm: 293T cells, MSC and tumor cells (TC) were transduced with lentiviral particles bearing RapaCasp9 (293T-RC9, MSC-RC9, GBM-RC9) or HSV-TK (293T-TK, MSC-TK, GBM-TK) genes along with Puromycin resistance gene for selection and Renilla Luciferase (Rluc) gene for detection in cytotoxicity assays (Figure 2a).