SIRT3 is not only involvedin cancer but also in infectious,26,27 heart,28 kidney,29 metabolic,30,31 and neurodegenerative diseasessuch as Alzheimer’s, Parkinson’s, and Huntington’sdisease, as well as in stroke and traumatic brain injury.32 A recent study by Yan et al. stated that SIRT3is very likely to play a crucial role in the development of neuropathicpain.33 Here, SIRT3 is linked to cancer.