GART and neoplasm: Emerging evidence has indicated that Wnt/β‐catenin signaling pathway mediates the tumorigenicity and metastasis of numerous tumor types through regulating cell stemness.[45, 46, 47] Based on the above analyses, the stemness mediated by GART in CRC cell lines and AOM/DSS‐induced primary tumor cells was examined using tumor sphere assay in vitro.