It has been reported that circMYO10 promotes osteosarcoma progression via the miR‐370‐3p/RUVBL1/β‐catenin/LEF1 complex axis.[53] The present study also showed that an elevated level of GART induced a high level of expression of RUVBL1 in CRC cells and tissues. Here, LEF1 is linked to osteosarcoma.