MAPT and Alzheimer disease: This is the first study to our knowledge of full‐scale analysis from all arms of the A/T/N framework, and the core findings of the prospective longitudinal study were as follows: (1) In terms of diagnostic accuracy for AD, the AUCs of CSF Aβ42/40 (CSF‐A), tau‐PET (neuroimaging‐T) and FDG–PET (neuroimaging‐N) were ranked as the top three ATN candidates in diagnosis accuracy for AD.