Baseline levels of CSF Aβ42/40 related with tau accumulation more strongly in subjects with MCI (r = −0.501, p = 0.000) and CN (r = −0.232, p < 0.001), while the association was markedly weaker among AD participants (r = −0.315, p = 0.096, Figure 4A). This evidence concerns the gene MAPT and Alzheimer disease.