MOG and myeloid sarcoma: These include (1) the absence of slowly expanding lesions which consist of an inactivated, demyelinated center with a rim of Iba1+ microglia/macrophages [41], and (2) high titers of anti-MOG antibody in serum [37], which play a role in MOG antibody disease (MOGAD) but are not thought to be involved in MS [18].