CSF1R and neoplasm: Interestingly, western blotting assay presented that compound 7 has a tris kinase inhibitory activity against CSF1R (colony-stimulating factor 1 (CSF-1), which is responsible for the enrollment of colony-stimulating factor-1 receptor (CSF-1R) stating macrophages that synthesize the prime cell kind through these gigantic tumor cells with IC50 equals to 13 nmol/L, KIT (c-Kit receptor tyrosine kinase) with IC50 value of 27 nmol/L, and FLT3-ITD with IC50 equals to 11 nmol/L (Table 2).