By performing immunohistochemistry analysis of human colorectal adenocarcinoma and matched adjacent normal tissues, we showed that nearly 70% of colorectal adenocarcinoma samples exhibited strong or extra‐strong positive staining for MLF2, whereas less than 5% of the adjacent normal colorectal tissues displayed strong positive MLF2 staining (Figure 6A,B). This evidence concerns the gene MLF2 and colorectal adenocarcinoma.