To better understand the underlying mechanism involved in the progression of NB cells, we performed RNA-seq and lipid metabolomics studies in ORF1 over-expression and FABP5 rescued cell lines, which showed that NBASP was involved in numerous biological processes and several signaling pathways, such as, MAPK signaling (Fig. 8a–d). The gene discussed is FABP5; the disease is neuroblastoma.