In a study done by Roh et al., to study the RGS1 expression in multiple myeloma BMB sections, they classified their patients into high versus low expression with a cutoff value 7 which is equivalent to 60%-70% expression, they found that this is the significant cutoff value in their population [11]. This may be related to the larger number of patients in their study and ethnic variation between the Asian and Egyptian populations. The gene discussed is RGS1; the disease is AL amyloidosis.