Regarding the biofunctional effects of tea-flower (‘Chaka’ in Japanese), we reported the antihyperlipidemic [58, 59], antihyperglycemic [59], GE inhibitory [59], gastroprotective [60], anti-obesity effects [61], and GIT accelerative [62] in vivo, along with antiallergic [63] and inhibitory effects on pancreatic lipase [62] and amyloid β (Aβ) aggregation [64] of the extract. This evidence concerns the gene PNLIP and obesity due to melanocortin 4 receptor deficiency.