KIF20A inhibited ferroptosis and induced oxaliplatin resistance in CRC cells by regulating the NUAK family kinase 1 (NUAK1)/PP1β/GPX4 signaling axis.[92] Overexpression of FAM98A increased cell proliferation and decreased ferroptosis by activating the translation of SLC7A11 in stress granules. This evidence concerns the gene GPX4 and colorectal carcinoma.