The peroxidase inhibited malignant tumor progression by inducing necroptosis through the autocrine production of TNF‐α and restoration of RIPK3 expression.[159] Fragile X mental retardation protein (FMRP) expression was notably increased in CRC tissues, and its inhibition induced necroptosis, thereby limiting carcinogenesis and progression. This evidence concerns the gene FMR1 and colorectal carcinoma.