SOCS2 improves HCC radiotherapy efficacy by promoting the ubiquitin‐mediated degradation of SLC7A11 and increasing ferroptosis.[105] A marked increase in stearoyl‐CoA desaturase 1 (SCD1) expression levels was detected in esophageal squamous cell carcinoma (ESCC), and this elevated expression was deemed a predictor of poor patient prognosis. This evidence concerns the gene SOCS2 and esophageal squamous cell carcinoma.