Furthermore, the combination of the two treatments inhibited cell migration, tumor growth, and lymph node metastasis.[70, 71] The treatment of CRC cells with IMCA inhibited cell viability and tumor growth by inhibiting the expression of SLC7A11, decreasing the content of cysteine and GSH, leading to the accumulation of ROS and inducing ferroptosis. This evidence concerns the gene SLC7A11 and colorectal carcinoma.