SLC1A1 and Anxiety: While most of these works relied on the use of Slc1a1-/- mice (Peghini et al., 1997), other studies that used overexpression models of EAAC1 showed behavioral abnormalities, including increased anxiety-like behaviors (Delgado-Acevedo et al., 2019; Escobar et al., 2021) and reduced responses to amphetamine-induced hyperlocomotion (Zike et al., 2017).