People with limitation of renal potassium excretion, such as patients with renal failure; those with diabetes mellitus; and those using potassium-sparing diuretics, angiotensin-converting enzyme inhibitors, or angiotensin receptor blockers, may experience cardiac arrhythmia and have an increased level of death risk after consuming excessive potassium [74]. The gene discussed is ACE; the disease is chronic obstructive pulmonary disease.