PDHA1 and epilepsy: There were four significantly different genes between control and epilepsy hippocampus samples, of which LIPT1 (log2 (fold change) = 1.34, p = 7.04 × 10−3) showed significantly higher expression while GLS (log2 (fold change) = −1.43, p = 1.03 × 10−2), PDHA1 (log2 (fold change) = −1.06, p = 3.01 × 10−3), and CDKN2A (log2 (fold change) = −1.94, p = 4.38 × 10−5) showed lower expression in TLE than controls (Figures 2A–C).