CYP11A1 and prostate carcinoma: The absence of an association between CYP11A1 (ttta)4 and prostate cancer development was confirmed in another study by Cicek et al. (2005); however, they were not able to corroborate Kumazama’s findings in which lack of CYP11A1 (tttta)4 was associated with increased stage and grade of prostate cancer.