Using Western blotting protein expression of HIF-1α was found to be increased under high salt diet (Li et al., 2008; Wang et al., 2010) and in DOCA/salt hypertension (Dallatu et al., 2014) and to be decreased in hypertension induced by nitric oxide synthase inhibition in combination with high salt diet (Dallatu et al., 2013). The gene discussed is HIF1A; the disease is Hypertension.