KLK3 and cancer: One study found that by subdividing patients with T1 cancer into groups of ranging percentages of infiltrative cancerous tissue (≤10%, >10 to ≤25%, >25 to ≤75%, and >75), it offered increased value and improved prediction compared to the current binary division and should be used along with other indicators of disease progression (i.e., PSA and Gleason grade) like grade in predicting cancer-related death [28].