APRIL/TNFSF13 and BAFF/TNFSF13B bind to the TACI/TNFSFR13B and BCMA/TNFSFR17 receptors, and play major roles in the recruitment, maturation, differentiation and survival of B cells, as well as the anti-tumor efficacy of DCs (11–13). Here, TNFRSF17 is linked to neoplasm.