CD4 and melanoma: According to the specific expression genes of 28 clusters, these clusters were labeled as melanoma cells (cluster 1, 4, 7, 8, 13, 14, 17, 19, 20, 22, 23, and 24), neural cells (clusters 15 and 25), fibroblasts (cluster 16), endothelial cells (cluster 26), NK cells (cluster 10), CD4+ T cells (clusters 0, 9), CD8+ T cells (clusters 2 and 3), B cells (cluster 18), plasma cells (clusters 12 and 21), monocytes and macrophages (clusters 5, 6, 27), and dendritic cells (cluster 11).