To reveal the ITH of melanoma, 10137 melanoma cells were further grouped into seven subtypes (C0 Melanoma BIRC7, C1 Melanoma CDH19, C2 Melanoma EDNRB, C3 Melanoma BIRC5, C4 Melanoma CORO1A, C5 Melanoma MAGEA4, and C6 Melanoma GJB2), each named based on the top marker. Here, BIRC5 is linked to melanoma.