Furthermore, we found that the highest regulon activity scores of melanoma cell subtypes in M1-M4 were C4 Melanoma CORO1A (M1), C4 Melanoma CORO1A (M2), C5 Melanoma MAGEA4 (M3), and C1 Melanoma CDH19 (M4), respectively. The gene discussed is CDH19; the disease is melanoma.