TUBA1A and Lissencephaly: Perturbations of TUBA1A cause a wide spectrum of lissencephaly and brain malformations which are often accompanied by motor impairment, epilepsy and cognitive deficits (Bahi-Buisson et al., 2014; Myers et al., 2015; Yokoi et al., 2015; Hebebrand et al., 2019; Xie et al., 2021; Schröter et al., 2022).