Overexpression of YEATS4 activates the-catenin/TCF signaling pathway and promotes the proliferation, invasion, and migration of pancreatic cancer cells (Figure 2H) (Jixiang, Shengchun, Jianguo, Zhengfa, Xin, Xuqing, et al.). This evidence concerns the gene HNF4A and familial pancreatic carcinoma.