In addition, the expression of RRM2 gene was also higher among the unhealed patients (n = 3) obtaining a significant p-value of 9.177E-05 with log2FC of 2.403 but failed to obtain a significant p-adjusted value that we taught might be due to small sample size and variation in infection severity among the unhealed patients when compared with healed patients (data not shown). Here, RRM2 is linked to infection.