In the healed group (n = 17), RRM2 and MYBL2 were significantly upregulated during active infection at 0 weeks but became downregulated at 8 weeks following therapy (p = 3.61E-07 and 2.7E-06 with corresponding FDR values of 0.001994 and 0.006835, respectively) (Figures 3F, G; Table 1). This evidence concerns the gene RRM2 and infection.