Up to now, the hypothesis chain regarding the regulatory network in our study has been completed, that is, transcriptional regulator WWTR1 up‐regulates the expression level of 3 PDEARGs, which may promote the excretion of TGF‐β, finally resulting in EMT‐mediated angiogenesis in GBM. Here, TGFB1 is linked to glioblastoma.