Eventually, a 12‐PDEARG prognostic signature consisting of MAPK1, ITGA5, NMD3, HEY1, COL6A1, DKK3, SERPINA5, NRP1, PLK2, ANXA1, SLIT2, PDPN was employed to calculate the risk score of GBM samples. Here, SLIT2 is linked to glioblastoma.