We compared the transcriptome data between normal samples and GBM tumor samples, which indicated that ANXA1, PDPN, COL6A1, BCL3, RUNX1, and WWTR1 were upregulated and compared to normal samples, BCL11A was downregulated in GBM tumor samples (Figure 6E). The gene discussed is PDPN; the disease is glioblastoma.