The association between cachexia stratified by the HF phenotype (HFrEF and HFpEF) and a high 2‐year mortality rate was retained even after adjusting the MAGGIC risk score and BNP (adjusted HRs and 95% CIs of the presence of cachexia: 1.493 [1.093–2.039], P = 0.012, in HFrEF and 1.519 [1.019–2.264], P = 0.040, in HFpEF). The gene discussed is NPPB; the disease is hydrops fetalis.