However, the analysis of 85 ccRCC patients, derived from the IMmotion 150 cohort (Sunitinib-treated), did not show significant differences in angiogenesis score between DKC1-high and low groups (P = 0.081), which was also the case in female (P = 0.129) and male (P = 0.303) patients (Fig. 6B). This evidence concerns the gene DKC1 and nonpapillary renal cell carcinoma.