The results showed that the protein expression levels of IRAK1 and TRAF6 were increased in the corneal epithelium and corneal stroma of the DE-group compared with those of the C-group, suggesting that IRAK1 and TRAF6 were involved in corneal inflammation in dry eye model mice (Fig. 2B). The gene discussed is TRAF6; the disease is Keratoconjunctivitis sicca.