As what is shown in Table 3, after adjusting for age, BMI, FBG, smoking, drinking, AST, ALT, γ-GT, TG, TP, Albumin, Globulin, CHOL, HDL, UA, BUN, hypertension, diabetic and fatty liver status, we found that compared with group Q1 (the first quartile of TBIL level), Q2 to Q4 of TBIL in total population were risk factors for fundus arteriosclerosis. This evidence concerns the gene ALB and Hypertension.