IRF5 (p=0.055), CCN1 (p=4.1e-08), MYC (p=0.039), POU5F1 (p=0.027), and TGFB1I1 (p=6.5e-08) were significantly differentially expressed at different stages of bladder cancer (Figure 3A). The gene discussed is IRF5; the disease is urinary bladder cancer.