Despite recent studies on TRIP13 in the human head and neck (Banerjee et al. 2014), prostate (Larkin et al. 2012), and colorectal cancers (Sheng et al. 2018) have suggested its involvement in drug resistance and carcinogenesis, the oncogenic function of TRIP13 in gastric malignancy remains largely unknown. This evidence concerns the gene TRIP13 and colorectal cancer.