To address this critical aspect of cancer diagnosis (and precision medicine), the fluorescent-IHC capacity of the αCSPG4(scFv)-SNAP fusion protein was demonstrated by its ability to specifically bind the CSPG4-expressing cells on FFPE tumor biopsies of South African TNBC patients, thereby distinguishing healthy from TNBC tissues based on superior expression levels of CSPG4 in the latter. Here, SNAP25 is linked to neoplasm.