In the fully adjusted model, which included pregnancy age, pregestational BMI, family history of T2DM, preceding history of GDM, gain in pregnancy weight, insulin use, fasting glucose at 10–14 weeks and glucose level 120 min after the OGTT during 24–28 weeks of pregnancy, lower quartiles were still related to a higher risk of postpartum AGM (adjusted OR 3.37 [95% CI 1.77–6.42], 2.42 [95% CI 1.29–4.51] and 2.27 [95% CI 1.23–4.18], respectively) than the highest quartile. The gene discussed is INS; the disease is gestational diabetes.