Variants in many genes associated with congenital muscular dystrophies (POMT1, POMT2, TRAPPC11, GOSR2) encode proteins that are localized to different membrane compartments of the vesicle trafficking pathway (Beltrán-Valero de Bernabé et al., 2002; van Reeuwijk et al., 2005; Bögershausen et al., 2013; Larson et al., 2018). This evidence concerns the gene GOSR2 and congenital muscular dystrophy.