The mixed treatment resulted in the most improved final measured values for HDLch, SBP, blood glucose (SO), DBP (SO) and ALT (NAFLD), and this was especially valid for patients with vitamin D deficiency, mainly for NAFLD cases with intensely altered investigated parameters, with the final effect of a clear improvement, spectacular and statistically significant for all parameters (except glycemia). The gene discussed is GPT; the disease is metabolic dysfunction-associated steatotic liver disease.