In a different study, Park et al. proposed that quercetin is a potent inhibitor of β-catenin/Tcf signaling in colon cancer SW480 cell lines and that decreased β-catenin/Tcf transcriptional ability is a result of reduced β-catenin (nuclear) and Tcf-4 proteins [127]. Here, HNF4A is linked to malignant colon neoplasm.