The crude and multivariable-adjusted ORs of T2D with synergistic effects on low antioxidant enzyme activities (SOD and CAT) versus the high levels were elevated by 2.44 fold (95% CI: 0.65–9.13) and 2.34 fold (95% CI: 0.52–10.43), respectively (Table 6). This evidence concerns the gene SOD1 and type 2 diabetes mellitus.