The intention of the research is to delve into the influence of MCF2L-AS1, miR-33a-5p and FGF2 on liver cancer cell proliferation, invasion, migration and apoptosis, as well as to examine the regulatory mechanism of the MCF2L-AS1-miR-33a-5p-FGF2 axis in the context of HCC. This evidence concerns the gene FGF2 and liver cancer.