To further determine the effects of IGF2BP1 on m6A‐modified eIF4G mRNA, we first knocked out IGF2BP1 in HCC cells and found that IGF2BP1 depletion strikingly reduced the protein abundance of eIF4G (Figure 6g), whereas IGF2BP1 overexpression obviously increased the protein abundance of eIF4G (Figure 6h). This evidence concerns the gene IGF2BP1 and hepatocellular carcinoma.