ALDOA and hepatocellular carcinoma: Furthermore, ectopic expression of eIF4G attenuated the decreases in cell viability and colony formation ability in ALDOA‐knockout cells (Figure S10f,g, Supporting Information), whereas treating ALDOA‐overexpressing HCC cells with SBI‐756 to impede protein biosynthesis dramatically dampened the enhancement of cell viability, colony formation ability and invasion capability induced by ALDOA overexpression (Figure S11, Supporting Information), indicating that eIF4G is a functional target of ALDOA in HCC cells.