In a study by Hernández-Alonso et al., people with prediabetes ate 57 g of pistachios per day for eight weeks, which resulted in improved insulin sensitivity and decreased expression of several genes (fibrinogen, platelet factor 4, oxidized LDL-c, Interleukin-6 mRNA, and resistin) [51]. The gene discussed is RETN; the disease is prediabetes syndrome.