The univariate and multivariate cox regression analysis (Supplemental Table S1) indicated that age, race, marital status, histologic type, grade, T stage, number of LNMM, ER, PR, HER2 status, and different type of adjuvant treatments were independent prognostic factors in the T1-2N1miM0 breast cancer population. This evidence concerns the gene PGR and breast cancer.