EPCAM and neoplasm: Their pro-tumoral function is linked to their cargo which comprises a plethora of pro-tumorigenic nucleic acids, lipids, and proteins (e.g. Wnt proteins, KRAS, EGFR, MMPs, EpCAM, HSP family members) which they can shuttle to surrounding tumor as well as stroma cells to foster transformation and aggressive phenotypes in recipient cells [13].