The three antigens separated breast cancer patients from healthy individuals with an AUC of 0.663 (95% CI: 0.504–0.821) for ROR1, 0.732 (95% CI: 0.586–0.878) for ROR2 and 0.652 (95% CI 0.489–0.814) for EpCAM. This evidence concerns the gene ROR2 and breast carcinoma.