Intrinsic pro- and anti-apoptotic scores for seven subclusters were calculated based on the expression of genes related to lung cancer cell intrinsic pro-apoptosis (BAX, BAK1, BAD, BIK, BID, BCL2L11, HRK, BBC3, and PMAIP1) or anti-apoptosis (BCL2, BCL2L1, BCL2L2, BCL2A1, and MCL1) [45]. This evidence concerns the gene PMAIP1 and lung cancer.