A previous study demonstrated that XIST promotes transforming growth factor-beta (TGF-β)-induced EMT which may regulate the miR-367/miR-141-ZEB2 axis in NSCLC [48], and our results showed that ZEB2 was highly expressed in the XIST+ tumor cells (Fig. 4G). The gene discussed is XIST; the disease is non-small cell lung carcinoma.