We further explored the link between CBX family and various immune markers for different immune cells in DLBCL through the TIMER 2.0 database, including monocytes, tumor-associated macrophages (TAMs), macrophages, neutrophils, NK cell, and dendritic cells, etc. After adjusting these results based on tumor purity, the expression levels of CBX1, CBX5, and CBX6 were significantly related to most of the immune markers of DLBCL tumor-infiltrating immune cells, and the results were consistent with the analysis of immune cell infiltration (Table 2). This evidence concerns the gene CBX6 and neoplasm.