The population distribution of 27 clinical indicators, including gender, age, BMI, rivaroxaban dose, antiplatelet drugs, hypertension, diabetes, high triglyceride, high cholesterol, LDL-cholesterol abnormal, lowest hemoglobin, lowest blood platelet, coronary disease, heart failure, valvulopathy, PCI, apoplexy, hemorrhage history, coagulopathy, TT, APTT, INR, D-dimer, AST, ALT, BUN and creatinine, is listed in Table 1. The gene discussed is GPT; the disease is blood coagulation disease.