In contrast, 1.0–1.2 pmol kg−1 min−1 of exogenous GLP-1 (7–36) amide normalised plasma glucose concentrations within 4–5 h in individuals with type 2 diabetes, starting with fasting hyperglycaemia during continued fasting [29, 31, 32, 41]. This evidence concerns the gene GCG and type 2 diabetes mellitus.