Similar outcomes indicated the ability of GAL to abate the expression of JAK/STAT3 in a model of colitis (Wazea et al. 2018), high-fat diet (Ashmawy et al. 2022), and AKI (Ibrahim et al. 2018) while improving SOCS3 expression in inflammatory bowel disease (Seyedabadi et al. 2018). This evidence concerns the gene SOCS3 and inflammatory bowel disease.