Next, we sorted ALDH-dim and ALDH-bright (ALDH-br) cell subpopulations from two ovarian cancer cell lines PEO1 and OVCAR3, and validated the enhanced expression of POLQ at the mRNA level in ALDH-br cells compared to ALDH-dim cells using qRT-PCR (Fig. 1c). Here, POLQ is linked to ovarian cancer.