We found that, in the same type of tumor cells, mice with tumors with relatively high ARIH1 expression (ARIH1-High) were more sensitive to PD-L1 treatment, with substantially reduced tumor growth and higher tumor inhibition rate compared to the group with relatively low ARIH1 expression (ARIH1-Low) (Supplementary Fig. 7d–k). The gene discussed is ARIH1; the disease is neoplasm.