ARIH1 mutations are found in 1.4% of breast cancer samples (n = 216; deep deletion)31, 2.9% of lung adenocarcinoma samples (n = 35; missense mutation)32, 2.0% of prostate cancer samples (n = 150; missense mutation)33 and 2.7% of melanoma samples (n = 110; missense mutation)34. This evidence concerns the gene ARIH1 and melanoma.