GFAP and Alzheimer disease: To determine whether Ngfr expression could enhance proliferation and neurogenesis of the astroglia in DG, we performed Lv13 and Lv16 transduction, BrdU labeling, and quantified the extent of labeled astroglia (Gfap+) and newborn neurons (Dcx+) at 3 days after transduction in wild type and APP/PS1dE9 mouse model of AD (Figs. 2, 3 and Supplementary Fig. 5).