NGFR and Alzheimer disease: Taken together, the human brain gene expression data support robust expression changes in AD brains in a direction congruent with the cross-species data, and evidence of neuronal and glial expression perturbations for PFKP, which is co-expressed with other microglial/endothelial and neuronal genes, respectively, and can mimic NGFR-induced neurogenic plasticity in astroglia.