Therefore, in this study, we want to estimate the levels of VD, SIRT1 and antioxidants (MnSOD, GR and visfatin) and oxidants (adrenaline & cortisol) in individuals living with infertility and explore the association of VD with SIRT1 expression (levels), antioxidants, and oxidants contributing to infertility in women. This evidence concerns the gene GSR and Infertility.